Counting Chromosomes: Not as Easy as 1, 2, 3

Counting Chromosomes: Not as Easy as 1, 2, 3

Mammalian cells must count their X chromosomes to determine whether to initiate X chromosome inactivation. A region that may be important for X chromosome counting has been identified, but the puzzle pieces still do not quite fit.

Sequencing medical therapy in prostate cancer: not as easy as 1-2-3.

In their article in this issue of ONCOLOGY, Drs. Hurwitz and Petrylak have very effectively reviewed recent progress in the treatment of advanced prostate cancer.[1] Enhanced understanding of the biologic drivers of disease progression and treatment resistance has led to prolific research, new therapeutic discoveries, and the timely approval of new agents. The authors note that currently the pr...

Easy as 1, 2, 3? Histamine receptors and gastric acid.

Ovarian follicle counts – not as simple as 1, 2, 3

Debate The functional life span of the ovaries is dictated in large part by the number of oocytes present, a number that is known to decline precipitously during both fetal development and postnatal life. Furthermore, studies from numerous laboratories have shown that exposure of the ovaries to a variety of pathological insults, such as anticancer therapies and environmental toxicants, accelera...

Costing nursing education programs. It's as easy as 1-2-3.

Staff development departments are pressured to reveal the costs of their educational programs and to compete with outside vendors for programming. The process of implementing a spreadsheet template for costing out staff development programs is described. The template is easy to use and supports "what if" analysis. This model allows educators to evaluate cost implications of curricular decisions...